“The Flight Attendant” starts as a romance that is quickly acidified by a night of alcohol-induced fun that results in a cruel, unsolved murder. At the heart of the show – which tackles everything from alcoholism to espionage – is a love story defined not by Cassie (Kaley Cuoco) and her one-night stand, Alex (Michiel Huisman), but by Cassie and her best friend on screen, Annie (Zosia Mamet). When filming started in 2019, their chemistry was unmatched. Two years and as many matching tattoos later, the BFFs are inseparable proof that good things can come out of hard times.
How Kaley Cuoco and Zosia Mamet met
During the casting process for “The Flight Attendant,” Cuoco and Mamet were asked to read a chemistry together, a hypothetically intimidating task that strengthened their jobs and their friendship. “Michiel [Huisman] and Kaley’s relationship, quite it’s a love story, but the real love story about [‘The Flight Attendant’] is Annie and Cassie, “Mamet told The Hollywood Reporter in June 2021.” When I heard they wanted me to [do a] chemistry read with Kaley, I thought, ‘Oh, they can see how important this relationship is’; you need a chemistry reading between two female best friends who have been best friends since they were kids. “
“It was this immediate spark of chemistry between the two of us.”
The chemistry reading was a success, giving both actors their seats as best friends on screen and laying the foundation for a years-long friendship. “I went into that room and they said, ‘You’re welcome to play,’” Mamet said. I pretended to be on my phone in the audition room, and Kaley went and slapped me on the nose, which was not in the script, and I immediately slapped her hand away like, “Do not.” I always say , [and] at that moment, Annie and Cassie were born. It was this immediate spark of chemistry between the two of us. . . We both just have this amazing sense of play and we love working together. I think we were our first lane [assistant director’s] existence because they literally had to be like, ‘OK, stop. Stop, we said cut! ‘ We just had so much fun together. “
Kaley Cuoco and Zosia Mamet as roommates
On the set, Cuoco and Mamet – whose characters on screen are more serious than silly – like to take turns making each other laugh, go from the script with bits and be loving in the form of hugs and countless “boops”. The unique bond between the friends became even stronger when Kuoco in September 2021 divorced her husband of three years, Karl Cook.
When he spoke to Kelly Clarkson on “The Kelly Clarkson Show” on April 28, Cuoco revealed that Mamet moved in with her shortly after the divorce to help her cope with her feelings, adding that it was difficult for her to open up at the beginning. “I tried to take on everything myself until I realized I couldn’t actually physically do it anymore,” she said. “Zosia is my teammate and my best friend. She pretty much lived with me the last few months of filming (season two), we just moved in together and I do not think I would have come to work a few days without her … “I never thought I would be addicted to anyone like that before, and I was really addicted to her. She helped me through so much.”
“Obviously, romantic relationships are important, but I think female friendships take it to another level.”
Becoming roommates turned out to be exactly what Cuoco and Mamet needed to strengthen their friendship, and the selfless gesture left a lasting impression on Cuoco. “She came to work on days she did not have to be there, and came and ate lunch with me,” she said. “I’m like ‘You have your day off today’ and she’s like ‘I’m coming in’ because she heard I was having a hard time and she wanted to sit in my trailer. She’s the best. I’m very lucky that I had her. “
In the same interview, Mamet explained that their friendship is unsurpassed. “I’m not super close to my family, and I’ve always found the chosen family so extraordinarily important,” she said. “I think, as women, [that friendship] is synonymous with anything. “Obviously, romantic relationships are important, but I think female friendships take it to another level.”
Kaley Cuoco and Zosia Mamet’s friendship
Most recently, friends have been everywhere on Instagram, posting heartfelt birthday messages to each other along with carousels of photos sharing a glimpse behind the scenes of their adorable friendship. “Happy birthday to this magical unicorn man,” Mamet wrote an Instagram post dedicated to Cuoco on November 30, 2021. “You’re one of a kind @kaleycuoco, I love you more than words can ever say. Now there a thousand more years of adventure and laughing together so hard our abdominal muscles hurt. You will always be Cassie for my Annie. “
In response, Cuoco shared a birthday tribute to Mamet on February 2nd. “Happy birthday to the princess unicorn fairy who is @zosiamamet !!” she wrote. “I’m so grateful you danced into my life and never left. You deserve the whole world. The kind, funny, sweet, empathetic, cute, ingenious way of touching you really touches everyone you meet. I am not sure what my life would look like over the last few months if you were not around and told me I was going to work and that it should probably go … I love you forever, sister wife. There’s no one like you my widdle smoosh !! 🎂 🎈 💋 🎁 you will always be Annie for my Cassie! Boop! “
As a tribute to their friendship and “The Flight Attendant”, Cuoco and Mamet got matching tattoos on paper airplanes together in October 2020. On April 19, they added another matching tattoo to their growing collection: “boop” with ink on their inner arms in honor for their meeting-sweet.
Cassie and Annie may be willing to help each other get away with murder, but Cuoco and Mamet’s IRL friendship is the right item. See more boop-worthy photos of the BFFs – including their time in the tattoo parlor – ahead.